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ea0041ep743 | Neuroendocrinology | ECE2016

Liraglutide restores the endocrine function of islet’s β-cells and the altered lipid profile in early stages of life induced by food restriction in pregnancy

Diz-Chaves Yolanda , Toba Laura , Fandino Juan , Ogando Hugo , Gonzalez-Nunez Maria , Romani Marina , Vigo Eva , Gonzalez-Matias Lucas , Mallo Federico

Maternal food restriction during late pregnancy and lactation, increases the risk of glucose intolerance and metabolic diseases such as diabetes & obesity in rats. Liraglutide is a GLP-1 receptor agonists administered for treating DM2. The aim of this study was to elucidate if liraglutide given to pregnant rats may prevent the deleterious effects of malnourishment in male pups analyzed at 21 days of age.Twenty eight Sprague-Dawley pregnant rats were ...

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Endocrine Abstracts

Liraglutide restores the endocrine function of islet’s β-cells and the altered lipid profile in early stages of life induced by food restriction in pregnancy

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